The Undieh Lab focuses on characterizing dopamine signaling and epigenetic remodeling in neuroplasticity, with applications to drug addiction, major depression, neurodegeneration, and spinal cord injury. This work aims to accelerate the development of strategies for preventing, diagnosing, and treating dopamine-associated disorders. Dr. Undieh is particularly interested in nucleolipid-mediated signaling cascades and their interactions with epigenetic mechanisms such as DNA methylation and microRNA regulation. Using integrative approaches, the lab correlates cellular-level genomic and neurochemical data with phenotypic and behavioral outcomes in organ systems or whole organisms, ensuring the physiological relevance of their findings.
Visit Dr. Undieh’s PubMed and ORCiD pages for research activity and publications.