The Kottmann Lab studies neuronal plasticity regulation during aging and Parkinson’s disease. Dr. Kottmann’s research has identified that inter-neuronal signaling pathways active during motor learning decline with aging and are disrupted in Parkinson’s disease. Dr. Kottmann and his team discovered that adjuvant dosing with Shh pathway agonists prevents disabling dyskinesia from L-Dopa treatment in murine and monkey models, aiming to develop drugs that replicate these effects in patients.
Visit Dr. Kottmann’s PubMed and ORCiD pages for research activity and publications.